Obstructing Trachea Tumor: Myoepithelial Carcinoma about a Case

Amine Kessab, Adil Zegmout, Mohammed Reda El Ochi, Wafaa El Omari, Abderrahmane Rhorfi, Mohamed Oukabli

Abstract


Myoepithelial carcinoma, also called malignant myoepithelioma, is an extremely rare tumor of the salivary gland type. It is defined as a malignant neoplasm in which the tumor cells exhibit exclusively myoepithelial differentiation. Our case is a 48-year-old patient with no specific history who was presented to the hospital emergency room for respiratory difficulty and dysphagia progressively evolving for 08 weeks. A cervical CT was done which revealed a hypodense tumor process in T1 of 4 cm long axis obstructing the trachea well limited and richly vascularized. The diagnosis of tracheal myoepithelial carcinoma was made after histological and immunohistochemical analysis on a biopsy pending analysis of the operative specimen. Treatment remains initially surgical with appropriate postoperative radiotherapy and chemotherapy.

Keywords


Myoepithelial, Trachea, Carcinoma, Biobsy, Histology

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References


- Tuncel U, Ergul G, Ozlugedik S, Unal A. Myoepithelial carcinoma in the nasopharynx: An unusual localization. Yonsei Med J 2004; 45: 161–5.

- Ibrahim R, Bird DJ, Sieler MW. Malignant myoepithelioma of the larynx with massive metastatic spread to the liver: An ultrastructural and immunocytochemical study. Ultrastruct Pathol 1991; 15: 69–76.

- Yu G, Qu G, Kong L, Pan X, Wang W, Lv J. Primary myoepithelial carcinoma of the larynx: Case report and review of the literature. Pathol Res Pract 2011; 207: 127–30.

- Travis WD, Fletcher CDM. Myoepithelial tumors / myoepithelial carcinoma. WHO Classification of Tumors of the Lung, Pleura, Thymus and Heart. 4th ed. 2015. P.131.

- J.G. Strickler, J. Hegstrom, M.J. Thomas, et al., Myoepithelioma of the lung, Arch.Pathol. Lab. Med. 111 (1987) 1082–1085

- X. Zhou, M. Yu, H. Zhuo, S. Zhang, Primary pulmonary myoepithelial carcinoma in a young woman: a case report and review of literature, Medicine (Baltimore) 97 (2018) e0049.

- Higashiyama M, Kodama K, Yokouchi H et al. Myoepithelioma of the lung: Report of two cases and review of the literature. Lung Cancer 1998; 20: 47–56.

- 13 Miura K, Harada H, Aiba S, Tsutsui Y. Myoepithelial carcinoma of the lung arising from bronchial submucosa. Am J Surg Pathol 2000; 24: 1300–4.

- Masuya D, Haba R, Huang CL, Yokomise H. Myoepithelial carcinoma of the lung. Eur J Cardiothorac Surg 2005; 28:775–7.

- Sarkaria IS, DeLair D, Travis WD, Flores RM. Primary myoepithelial carcinoma of the lung: A rare entity treated with parenchymal sparing resection. J Cardiothorac Surg 2011; 6: no. 27.

- Yuan L, Jian W , Hecheng L, Xiongzeng Z and Lei S, Myoepithelial carcinoma: First case reported in the trachea Pathology International 2012; 62: 55–59

- K. Khazeni, H. LaBove, B. Wilky, et al., Myoepithelial carcinomor epithelioid sarcoma – A rare diagnosis with poor prognosis. A case report and review of literature, Int. J. Surg. Case Rep. 49 (2018) 239–243.

- K. Thway, N. Bown, A. Miah, et al., Rhabdoid variant of myoepithelial carcinoma, with ewsr1 rearrangement: expanding the spectrum of EWSR1-rearranged myoepithelial tumors, Head Neck Pathol. 9 (2015) 273–279.

- A. Skálová, I. Weinreb, M. Hyrcza, et al., Clear cell myoepithelial carcinoma of salivary glands showing EWSR1 rearrangement: molecular analysis of 94 salivary gland carcinomas with prominent clear cell component, Am. J. Surg. Pathol. 39 (2015) 338–348




DOI: http://dx.doi.org/10.7575/aiac.abcmed.v.9n.3p.45

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